Iontophoresis Side Effects
Iontophoresis is the use of an ionic solution e.g. tap water, and electricity in order to prevent sweating in the applied areas. Nobody knows 100% how or why it works but it seems to stop sweating for at least a few days to up to a few weeks depending on the solution used, frequency of use, voltage etc.
If you’ve just started iontophoresis or you’re considering it, it’s natural to question if there are any potential side effects of the treatment. Let’s delve further into this matter.
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There’s much argument as to whether this is really a side effect or not. The iontophoresis treatment is the application of an electric current to a liquid solution into which you place your hands, feet or some other part of the body e.g. the armpits.
A unique sensation can definitely be felt. It is not the same as a sudden high voltage electric shock and most people describe it as a tickling or “pins and needles” sensation, rarely as a “burning” sensation. If the voltage is turned too high then this could be painful. But either way, it is a matter of contention as to whether this constitutes a real side effect or not.
In particular, it is wise to conver any open wounds (simply with petroleum jelly) as these sites may be painful during the electrolysis procedure.
Other Dermal Effects
Vesiculation (like small bubbles in the skin) can occur but usually passes quickly. It affects less than 10% of all people having this procedure. Redness of the skin at the waterline is fairly common but minor and again, passes fairly quickly.
Best Practice
Anyone who undergoes regular iontophoresis sessions should keep their hands well moisturised to avoid cracking and open wounds. If they do this then they can expect minimal side effects, if any at all.

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